Table 1.
Participant characteristics (N = 101)
| Variables | NCI− N = 42 |
NCI+ n = 59 |
Statistic |
|---|---|---|---|
| Demographic characteristics | |||
| Age, mean (SD) | 42.1 (9.7) | 40.9 (9.5) | t(99) = 0.52 |
| Male, n (%) | 28 (66.7) | 46 (78.0) | X2(1) = 1.60 |
| African-American race, n (%) | 29 (69.1) | 53 (89.8) | X2(1) = 6.94** |
| Current substance use | |||
| Daily cigarette smoking, n (%) | 20 (47.6) | 34 (57.6) | X2(1) = 0.99 |
| Alcohol, n (%) | 38 (90.5) | 43 (72.9) | p = 0.04* |
| Cocaine, n (%) | 14 (33.3) | 17 (28.8) | X2(1) = 0.24 |
| Marijuana, n (%) | 17 (40.5) | 24 (40.7) | X2(1) = 0.00 |
| HIV characteristics | |||
| Years since HIV diagnosis, median (IQR) | 8.4 (5.2, 15.5) | 8.0 (3.7, 17.6) | S = 2239 |
| Recent CD4+ T cell counts, median (IQR) | 711 (480, 857) | 513 (300, 860) | S = 2329 |
| Nadir CD4+ T cell counts, median (IQR) | 305 (105, 500) | 228 (100, 386) | S = 2274 |
| Recent viral load < 50 copies/ml, n (%) | 31 (75.6) | 44 (75.9) | X2(1) = 0.01 |
| Other clinical characteristics | |||
| Hemoglobin (g/dl), median (IQR) | 14.4 (13.4–5.3) | 13.6 (12.6, 14.8) | S = 2142* |
| FIB-4, median (IQR) | 1.0 (0.7, 1.3) | 1.0 (0.7, 1.3) | S = 1859 |
| eGRF > 60 ml/min, n (%) | 35 (89.7) | 51 (94.4) | p = 0.45* |
| Chronic HCV infection, n (%) | 3 (7.1) | 9 (15.5) | p = 0.23 |
| Albumin (g/dl), median (IQR) | 4.1 (3.8, 4.4) | 3.9 (3.6, 4.2) | S = 1741* |
| WBC (103 cells/ml), median (IQR) | 6.0 (4.5, 7.0) | 5.3 (4.6, 6.8) | S = 1654 |
| BMI, mean (SD) | 25.8 (22.5, 30.7) | 25.4 (21.9, 28.1) | S = 2262 |
| VACS index, median (IQR) | 39.9 (32.2, 47.0) | 46.7 (29.8, 57.5) | S = 1966 |
BMI body mass index, IQR interquartile range, NCI neurocognitive impairment, SD standard deviation, VACS veterans aging cohort study, WBC white blood count
*
P < 0.05
**
P < 0.01