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. 2021 Mar 4;7(3):183. doi: 10.3390/jof7030183

Table 2.

The order of allergen reagents (allergenic extracts and molecular components) according to the frequency in 100 atopic dermatitis patients (it is shown the sensitization in the frequency 10% and more). The sensitization to molecular components of molds and yeast (Mala s 5, Mala s 6, Mala s 11, Sac c, Alt a 1, Alt a 6, Asp f 1, Asp f 3, Asp f 4, Asp f 6, Cla h 8 and Pen ch) is recorded extra bold *. Low sensitization rate was observed to Asp f 1, Asp f 4 and to Pen ch (Penicillium chrysogenum) in 3–4% of patients.

Allergen Reagents
(Allergenic Extracts and Molecular Components)
Frequency in %
Phl p 1 (Beta-expansin, Timothy grass) 57.0
Bet v 1 (PR-10 protein, birch),
Lol p 1 (Beta-expansin, Rye grass),
Sec c_pollen (cultivated rye, pollen)
53.0
Fag s1 (PR-10 protein, European beech) 49.0
Cor a 1.0103 (PR-10 protein, hazel pollen)
Cyn d 1 (Beta-expansin, Bermuda grass)
48.0
Cor a_pollen (hazel pollen) 47.0
Der f 2 (NPC2 family, house dust mite)
Fra a 1+3 (PR 10 protein + Non-specific lipid transfer protein, type 1, strawberry)
Phl p 2 (Expansin, Timothy grass)
45.0
Cor a 1.0401 (PR-10 protein, hazel pollen)
Cyn d (Bermuda grass)
Der p 2 (NPC2 family, house dust mite)
Fel d 1 (Uteroglobin, cat)
44.0
Aln g 1 (PR-10 protein, alder) 43.0
Pas n (Bahia grass)
Phl p 5.0101 (Grass Group 5/6, Timothy grass),
Phl p 6 (Grass Group 5/6, Timothy grass)
42.0
Lep d 2 (NPC2 family, storage mite)
Mal d 1 (PR-10 protein, apple)
41.0
Can f 1 (Lipocalin, dog)
Der p 23 (Peritrophin-like protein domain, house dust mite)
36.0
Gly m 4 (PR-10 protein, soybean) 35.0
Der p 1 (Cysteine protease, house dust mite) 34.0
Ara h 8 (PR-10 protein, peanut)
Gly d 2 (NPC2 family, storage mite)
33.0
Art v (Mugwort), Can f 6 (Lipocalin, dog) 32.0
Der f 1 (Cysteine protease, house dust mite)
Fel d 7 (Lipocalin, cat)
31.0
Can f_male urine (male dog urine) 30.0
Can f 4 (Lipocalin, dog)
Equ c 1 (Lipocalin, horse)
29.0
Pla l (English plantain) 28.0
Ory c 3 (Uteroglobin, rabbit)
Phr c (Common reed)
27.0
Aca s (storage mite)
Alt a 1 (unknown, Alternaria alternata) *
Der p 5 (unknown, house dust mite)
Fel d 4 (Lipocalin, cat)
26.0
Amb a (ragweed)
Tyr p (storage mite)
25.0
Ach d (house cricket)
Der p 7 (Mites group 7, Bactericidal permeability-increasing-like protein, house dust mite)
Loc m (Migratory locust)
Mala s 11 (Mn superoxide dismutase, Malassezia sympodialis) *
24.0
Amb a 4 (Plant defensin, ragweed)
Der p 20 (Arginine kinase, house dust mite),
Ten m (Mealworm)
23.0
Api g 1 (PR-10 protein, celery), Mus m 1 (Lipocalin and urinary prealbumin, house mouse) 22.0
Bla g 9 (Arginine kinase, German cockroach)
Can f_Fd1 (Uteroglobin, dog),
Cav p 1 (Lipocalin, Guinea pig)
21.0
Asp f 6 (Mn superoxide dismutase, Aspergillus fumigatus) *
Bla g 4 (Calycin, Lipocalin, German cockroach)
Fra e 1 (Ole e 1-like protein family, European ash),
Jug r_pollen (walnut pollen)
20.0
Art v 1 (Plant defensin, Mugwort)
Dau c (Carrot)
Dau c 1 (PR-10 protein, carrot)
19.0
Par j 2 (Non-specific lipid transfer protein, type 1, Pellitory of the wall)
Pen m 2 (Arginine kinase, shrimp)
Ves v 5 (Antigen 5, Yellow jacket venom)
18.0
Ama r (redroot pigweed)
Can f 2 (Lipocalin, dog)
Rat n (rat)
17.0
Api m (Honey bee venom)
Cup a 1 (Pectate Lyase, cypress)
Fra e (European ash),
Gal d_white (egg white)
Per a (American cockroach)
16.0
Aca m (Acacia)
Api m 1 (Phospholipase A2, Honey bee venom)
Asp f 3 (Peroxysomal protein, Aspergillus fumigatus) *
Cla h 8 (Mannitol dehydrogenase, Cladosporium herbarum) *
Cry j 1 (Pectate lyase, Japanese cedar)
Der p 21 (unknown, house dust mite)
Hel a (sunflower seed)
Hom g (lobster)
Pla l 1 (Ole e 1-like protein family, English plantain)
Sal k (Russian thistle, saltwort)
15.0
Act d 2 (Thaumatin-like protein, kiwi fruit)
Mala s 6 (Cyclophilin, Malassezia sympodialis) *
Sac c (Saccharomyces cerevisiae) *
Sol t (potato)
14.0
Api m 10 (Icarapin Variant 2, Honey bee venom)
Pha v (Green bean, French bean)
13.0
Alt a 6 (Enolase, Alternaria alternata) *
Amb a 1 (Pectate lyase, ragweed),
Api g 2 (Non-specific lipid-transfer protein, type 1, celery)
Blo t 5 (Mites group 5, storage mite)
Can s (hemp), Hor v (barley)
Lol spp. (squid)
Pan b (Northern shrimp),
Phl p 7 (Polcalcin, Timothy grass)
Phod s 1 (Lipocalin, Siberian hamster)
Sal k 1 (Pectin methylesterase, Russian thistle, saltwort)
Urt d (nettle)
12.0
Bet v 2 (Profilin, birch)
Cuc m 2 (Profilin, muskmelon)
Pec spp. (Scallop)
Sec c_flour (cultivated rye)
Ses i 1 (2S albumin, sesame)
Tyr p 2 (NPC2 family, storage mite)
Ves v (Yellow jacket venom), Ves v 1 (Phospholipase A1, Yellow jacket venom)
Zea m 14 (Non-specific lipid transfer protein, type 1, maize)
11.0
Che q (quinoa)
Mala s 5 (unknown, Malassezia sympodialis) *
Ole e 1 (Ole e 1-family, olive)
Pers a (avocado)
Phl p 12 (Profilin, Timothy grass)
Pla a 2 (Polygalacturonase, London plane tree)
Pol d (paper wasp venom)
Pyr c (pear)
Sola l (tomato)
Ulm c (Elm)
Zea m (Maize)
10.0