Table 3.
The sensitization rate to molecular components of yeast and molds in 100 atopic dermatitis patients. We show the number of positive results of specific IgE in the whole group of patients and in patients suffering from mild, moderate and severe form of AD (relative frequency of sensitization rate is recorded in %). The significance level was set to 5%. The significant difference (p-value <0.05) is shown extra bold *, (the statistical analysis is made with Fisher´s exact test).
| Number of Patients (%) with Positive Results of Specific IgE in the Whole Study—100 Patients (=100%) | Severity of Atopic Dermatitis | ||||
|---|---|---|---|---|---|
| Yeast | Mild Form 14 Patients (=100 %) |
Moderate Form 61 Patients (=100 %) |
Severe Form 25 Patients (=100 %) |
p-Value | |
|
Mala s 5
Malassezia sympodialis |
10 (10.0%) | 0 | 5(8.2%) | 5 (20.0%) | 0.123 |
|
Mala s 6 Malassezia sympodialis, Cyclophilin, |
14 (14.0%) | 0 | 6 (9.8%) | 8 (32.0%) | 0.011 * |
|
Mala s 11 Manganese superoxide dismutase, Malassezia sympodialis |
24 (24.0%) | 0 | 11 (18.0%) | 13 (52.0%) | 0.001 * |
|
Sac c
Saccharomyces cerevisiae |
14 (14.0%) | 0 (0%) | 6 (9.8%) | 8 (32.0%) | 0.011 * |
| Moulds | |||||
|
Alt a 1
Alternaria |
26 (26.0%) | 3 (21.4%) | 16 (26.2%) | 7 (28.0%) | 0.949 |
|
Alt a 6 Enolase, Alternaria alternata |
12 (12.0%) | 0 | 6 (9.8%) | 6 (24.0%) | 0.073 |
|
Asp f 1 Aspergilus fumigatus Mitogillin family |
4 (4.0%) | 0 | 1(1.6%) | 3 (12%) | 0.098 |
|
Asp f 3 Aspergilus fumigatus Peroxysomal protein |
15 (15.0%) | 0 | 8 (13.1%) | 7 (28.0%) | 0.055 |
|
Asp f 4 Aspergilus fumigatus |
3 (3.0%) | 1 (1.7%) | 0 | 2 (8.0%) | 0.057 |
|
Asp f 6 Aspergilus fumigatus Mn superoxide dismutase |
20 (20.0%) | 0 | 10(16.4%) | 10 (40.0%) | 0.007 * |
|
Cla h
Cladosporium herbarum |
6 (6.0%) | 0 | 1 (1.6%) | 5 (20.0%) | 0.008 * |
|
Cla h 8 Mannitol dehydrogenase, Cladosporium herbarum |
15 (15.0%) | 0 | 7(11.5%) | 8(32.0%) | 0.017 * |
|
Pen ch
Penicillium chrysogenum |
3 (3.0%) | 0 | 1(1.6%) | 2 (8.0%) | 0.204 |