Table 3.
Demographic and preoperative data in the 4 age-subgroups.
| Group | A | B | C | D | Total | p Value |
|---|---|---|---|---|---|---|
| Age (years) | ≤49 | 50–64 | 65–79 | ≥80 | 18–91 | |
| Number | 122 | 111 | 66 | 34 | 333 | |
| Onset > 72 h | 59.8% | 69.4% | 75.8% | 79.4% | 68.2% | p = 0.007 (1) |
| Female (%) | 29.5% | 29.7% | 36.4% | 26.5% | 30.6% | p = 0.716 (2) |
| Severity forms TG13/TG 18 | ||||||
| Mild | 36.10% | 27% | 22.70% | 11.80% | 27.90% | p < 0.001 (1) |
| Moderate | 61.50% | 68.50% | 65.20% | 70.60% | 65.50% | |
| Severe | 2.50% | 4.50% | 12.10% | 17.60% | 6.60% | |
| Leukocytes ≥ 18,000/mmc | 2.5% | 7.2% | 12.1% | 14.7% | 7.2% | p = 0.025 (2) |
| Fibrinogen > 400 mg/dL | 34.4% | 48.6% | 60.6% | 67.6% | 47.7% | p = 0.007 (1) |
| Creatinine > 1.2 mg/dL | 19% | 19.8% | 37.9% | 50% | 26.2% | p < 0.001 (1) |
| Aspartate transaminase (AST), Alanine transaminase (ALT) > 40 UI/L | 33.6% | 38.7% | 28.8% | 47.1% | 35.7% | p = 0.268 (2) |
| INR(international normalized ratio) > 2 | 0 | 2.7% | 0 | 5.9% | 1.5% | p = 0.039 (2) |
| Bilirubin > 1.2 mg/dL | 11.4% | 9.9% | 24.2% | 29% | 15.31% | p = 0.045 (2) |
| Sign of acute cardiac insufficiency at admission *** | 2.5% | 9.9% | 21.2% | 44.1% | 12.9% | p < 0.001 (1) |
| Neurologic decompensation at admission | 0 | 0 | 0.015% | 0.029% | 0.006% | N/A |
| ASA PS risk | ||||||
| I | 33.60% | 18% | 6.10% | 0 | 19.50% | p < 0.001 (1) |
| II | 54.10% | 57.70% | 53% | 44.10% | 54.10% | |
| III | 12.30% | 20.70% | 37.90% | 44.10% | 23.40% | |
| IV | 0 | 2.70% | 3% | 8.80% | 2.40% | |
| V | 0 | 0.90% | 0 | 2.90% | 0.60% | |
| CCI | ||||||
| 0 | 88.40% | 60.30% | 28.70% | 20.50% | 58.80% | p < 0.001 (1) |
| 1 | 5.70% | 14.40% | 27.20% | 26.50% | 15.30% | |
| 2 | 1.60% | 14.10% | 21.20% | 20.60% | 8.40% | |
| 3 | 5.70% | 11.70% | 12.10% | 8.80% | 9.30% | |
| 4 | 1.60% | 3.60% | 4.50% | 14.70% | 5.10% | |
| 5 | 0 | 1.80% | 3% | 0 | 1.20% | |
| ≥6 | 0.80% | 1.80% | 0 | 8.80% | 1.80% |
Footnote: (1) Test of Linear-by-Linear Association; (2) Fisher’s exact test; ASA PS: American Society of Anesthesiologists Physical Status Classification; TG13/18: Tokyo Guidelines classification risk; CCI: Charlson Comorbidity Index. *** described according to Common Guide of diagnostic and treatment of Acute Cardiac Insufficiency of European Society of Intensive Therapy and European Society of Cardiology: (i) Aggravated preexisting cardiac insufficiency (edema of the lower limbs, congestion); (ii) Hypertensive Cardiac insufficiency (high BP, tachycardia, signs of vasoconstriction); (iii) Pulmonary acute edema: acute respiratory disfunction, with tachypnea and orthopnea, SaO2 < 90% before oxygen administration; (iv) Acute coronary syndrome; (v) Cardiogenic shock: hypotension requiring vasopressor medication, signs of organ hypoperfusion, with oliguria.