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. 2021 Mar 13;12(3):414. doi: 10.3390/genes12030414

Table 2.

Summary of the significantly expressed miRNAs in chicken abdominal fat.

miRNA Function References
Gga-let-7a

  • Highly abundant differentially expressed miRNAs in the chicken abdominal fat

 [41,65]
Gga-let-7j
Gga-let-7b
Gga-let-7f
Gga-let-7c
Gga-let-7k
Gga-miR-148a-3p

  • Abundant miRNA in abdominal fat of lean broiler lines

  • Promote adipogenesis by targeting WNT1

 [27,65]
Gga-miR-146c

  • Involve in chicken preadipocyte development and metabolism

 [65]
Gga-miR-10a
Gga-miR-33
Gga-miR-222
Gga-miR-15a
Gga-miR-22
Gga-miR-206
Gga-miR-1a
Gga-miR-29b
Gga-miR-9
Gga-miR-32
Gga-miR-429

  • Regulate adipogenesis
Gga-miR-200b
Gga-miR-451
Gga-miR-142-5p
Gga-miR-200a
Gga-miR-218
Gga-miR-454
Gga-miR-30a-5p [27]
Gga-miR-122-5p

  • Adipose-related miRNA

  • Involve in growth and development of adipose tissue by targeting PPARγ

  • Its abundance affects the PPAR signaling pathway and adipocyte differentiation

 [67]
Gga-miR-19b-3p

  • Promoting preadipocyte proliferation and adipocyte differentiation by downregulation of ACSL1

 [14]
Gga-miR-19a-3p

  • Involve in regulating the accumulation of abdominal fat in chicken
Gga-miR-17-5p
Gga-miR-26a
Gga-miR-103-3p
Gga-miR-92-3p
Gga-miR-34 Have key roles in:

  • Lipid metabolism

  • Adipocyte proliferation and differentiation

  • Cell junctions during abdominal adipose tissue development in chicken

 [27]
Gga-miR-199
Gga-miR-8
Gga-miR-146b-5p
Gga-miR-17-3p

  • Promote adipocyte differentiation by targeting fatty acyl desaturase gene
Gga-miR-215-5p

  • Differentially expressed miRNAs in different stages of abdominal adipose tissue development
Gga-miR-499-5p
Gga-miR-135a

  • MiRNAs with developmental stage-specificity

  • Regulate adipocyte differentiation
Gga-miR-21

  • Inhibit chicken preadipocyte proliferation by downregulating KLF5

  • Abundant miRNA in abdominal fat of fat broiler lines

  • Regulate adipogenesis

 [9,27,53,65]
Gga-miR-101-3p

  • Regulate adipogenesis

  • Involve in chicken preadipocyte development and metabolism

 [27,65]
Gga-miR-31

  • MiRNA with developmental stage-specificity

  • Regulate adipocyte differentiation

  • Involve in chicken preadipocyte development and metabolism

 [27,65]
Gga-miR-30d
Gga-miR-27-3p

  • Regulate adipogenesis

  • Involve in regulating the accumulation of abdominal fat in chicken

 [14,27]