Table A2.
Phenotypic resistance testing of the Acinetobacter spp. isolates based on micro-broth dilution (applied for colistin) and automated resistance testing using a VITEK-II device (BioMéreux, Nürtingen, Germany; applied for all other assessed antimicrobial substances). MICs (minimum inhibitory concentrations) in µg/mL are shown in brackets. Interpretation was performed according to EUCAST NAK (European Committee on Antimicrobial Susceptibility Testing “Nationales Antibiotia-Sensitivitätstest-Kommittee”). S = susceptible. I = Susceptible at increased dosage. R = Resistant. N.d. = not defined.
| Strain Number | Species | Imipenem | Meropenem | Amikacin | Gentamicin | Tobramycin | Ciprofloxacin | Cotrimoxazole | Colistin |
|---|---|---|---|---|---|---|---|---|---|
| Iraq-2 | A. baumannii | R (8) | I (8) | S (≤2) | R (8) | S (4) | R (≥4) | R (160) | S (0.0625) |
| AFG-1 | A. baumannii | R (≥16) | R (≥16) | S (≤2) | S (4) | S (2) | R (≥4) | R (≥320) | S (0.5) |
| AFG-2 | A. baumannii | R (≥16) | R (≥16) | S (≤2) | S (4) | S (≤1) | R (≥4) | R (≥320) | S (0.25) |
| AFG-3 | A. baumannii | R (8) | I (8) | S (8) | S (4) | S (2) | R (≥4) | R (≥320) | S (2) |
| AFG-4 | A. baumannii | R (8) | R (≥16) | S (≤2) | S (4) | S (≤1) | R (≥4) | R (≥320) | S (1) |
| HBG-L1-1 | A. baumannii | R (≥16) | R (≥16) | S (≤2) | R (≥16) | R (≥16) | R (≥4) | R (≥320) | S (0.5) |
| HBG-L2-9 | A. baumannii | R (≥16) | I (8) | S (≤2) | R (8) | R (8) | R (≥4) | R (≥320) | S (0.5) |
| WEST-S6-47 | A. baumannii | I (1) | I (4) | R (≥64) | R (8) | R (8) | R (≥4) | R (≥320) | S (1) |
| WEST-S1-31 | A. baumannii | R (≥16) | R (≥16) | S (4) | R (≥16) | R (≥16) | R (≥4) | R (≥320) | S (0.5) |
| WEST-S6-50 | A. baumannii | R (≥16) | R (≥16) | S (4) | R (≥16) | R (≥16) | R (≥4) | R (≥320) | S (1) |
| HBG-S4-64 | A. baumannii | R (≥16) | R (≥16) | S (8) | R (≥16) | R (≥16) | R (≥4) | S (≤20) | S (0.25) |
| HBG-S1-56 | A. baumannii | R (≥16) | R (≥16) | S (≤2) | S (4) | S (≤1) | R (≥4) | S (≤20) | S (0.125) |
| HBG-S7-73 | A. baumannii | R (≥16) | R (≥16) | S (4) | R (≥16) | R (≥16) | R (≥4) | S (≤20) | S (0.25) |
| HBG-S2-62 | A. baumannii | R (≥16) | R (≥16) | R (16) | R (≥16) | R (≥16) | R (≥4) | R (≥320) | S (1) |
| WEST-S5-44 | A. radioresistens | S (≤0.25) | S (≤0.25) | S (≤2) | S (≤1) | S (≤1) | I (≤0.25) | S (≤20) | S (0.5) |
| Iraq-1 | A. dijkshoorniae | S (≤0.25) | I (4) | S (≤2) | S (≤1) | S (≤1) | I (0.5) | S (≤20) | S (0.125) |