Figure 10.

Expression of different functional molecules on Treg cells during cultivation. Anti-CD3 + IL-2 stimulation increased the expression of assessed functional molecules of Treg cells in both HDs and RA patients in a similar manner. By contrast, stimulation with homeostatic cytokines increased only the density of PD-L1 expression in both groups. Median and IQR. Unrelated groups were compared using the Mann–Whitney test. A comparison of related groups was performed using the Friedman test (ANOVA), and post hoc analysis was performed using the Dunn test; RA, rheumatoid arthritis (n = 9); HDs, healthy donors (n = 9).