Table 1.

Sensitivity of 5-fluorouracil in the parental HCT116, HCT116R^F3 and HCT116R^F10 cells.

Cell line	EC50 (M)		RI
	WST-8 Assay	CFA	WST-8 Assay	CFA
HCT116	5.1 × 10−6	5.5 × 10−6	1	1
HCT116RF3	1.5 × 10−5	1.6 × 10−5	2.9	2.9
HCT116RF10	2.9 × 10−5	3.8 × 10−5	5.7	6.9

Note. EC₅₀, 50% effective concentration; R, resistant; F3, fluorouracil 3 × 10⁻⁶ M; F10, fluorouracil 10 × 10⁻⁶ M; RI, resistance index.