Table 1.

Summary of single-cell omics studies on the immune system cells in the brain including microglia. Blue squares indicate that study included cells from a given condition. MS—multiple sclerosis, ALS—amyotrophic lateral sclerosis, EAE—experimental autoimmune encephalitis, HD—Huntington’s disease, AD—Alzheimer’s disease, MDD—major depressive disorder.

	Healthy Brain	Epilepsy (Non-Pathological Tissue)	Brain Tumor	Aged Brain	MS	ALS	EAE	HD	AD	MDD	LPS Injection	Neurodegeneration	Microglia Depletion	Species	Number of Cells scRNA-seq	Number of CyTOF Antibodies
Korin et al. 2017 [62]														mouse	—	44
Li et al. 2019 [63]														mouse	1816	—
Böttcher et al. 2019 [64]														human	—	57
Geirsdottir et al. 2019 [65]														various	4458	—
Darmanis et al. 2017 [66]														human	3589	—
Venteicher et al. 2017 [67]														human	14,226	—
Müller et al. 2017 [68]														human	1373	—
Friebel et al. 2020 [69]														human	—	74
Ochocka et al. 2021 [70]														mouse	40,401	—
Sankowski et al. 2019 [71]														human	6411	55
Mrdjen et al.. 2018 [20]														mouse	—	43
Keren-Shaul et al. 2017 [72]														mouse	11,841	—
Dulken et al. 2019 [73]														mouse	14,685	—
Hammond et al. 2018 [74]														mouse	76,149	—
Esaulova et al. 2020 [75]														human	≈30,000	—
Ajami et al. 2020 [75]														mouse	—	255
Jordão et al. 2019 [76]														mouse	3461	—
Mathys et al. 2017 [77]														mouse	1685	—
Mathys et al. 2019 [78]														human	75,060	—
Olah et al. 2020 [79]														human	16,242	—
van Hove et al. 2019 [80]														mouse	25,384	—
Böttcher et al. 2020 [81]														human	—	59
Sousa et al. 2018 [82]														mouse	1247	—
Tay et al. 2018 [83]														mouse	944
Masuda et al. 2019 [84]														mouse/human	5428	—
Huang et al. 2019 [85]														mouse	1194	—