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. 2021 Mar 16;10(6):1224. doi: 10.3390/jcm10061224

Table 3.

Sensitivity, specificity, positive predictive value (PPV), positive negative value (PNV), accuracy and likelihood ratio of the four diagnostic modalities applied in group B.

Indicator NBI WLE 1 + 2 WLE 2 WLE 1 + 2 and NBI
Sensitivity 82.4 % 88.3 % 64.7 % 76.5 %
Specificity 94.1 % 29.4 % 85.3 % 94.1 %
PPV 87.5 % 38.4 % 68.7 % 86.7 %
NPV 91.4 % 83.3 % 82.8 % 88.9 %
Accuracy 90.2 % 49.0 % 78.4 % 88.2 %
Positive likelihood ratio 13.96 1.25 4.40 12.97
Negative likelihood ratio 0.18 0.40 0.41 0.25
Mode Area Lower limit 95% CI Upper limit 95% CI p
NBI 0.88 0.78 0.98 <0.0001
WLE 1 + 2 0.58 0.47 0.69 <0.0001
WLE 2 0.75 0.62 0.88 <0.0001
WLE 1 + 2 and NBI 0.85 0.74 0.96 <0.0001
Mode comparison z Lower limit 95% CI Upper limit 95% CI p
WLE 1 + 2 vs. WLE 2 −2.365 0.347 −0.296 0.018
WLE 1 + 2 vs. NBI −3.714 0.330 −0.449 <0.0001
WLE 1 + 2 vs. WLE + NBI −3.674 0.335 −0.406 <0.0001
WLE 2 vs. NBI −1.842 0.342 −0.273 0.066
WLE 2 vs. WLE + NBI −1.532 0.348 −0.235 0.126
NBI vs. WLE + NBI 1.000 0.322 −0.028 0.317

CI: confidence interval; NBI: narrow band imaging; NPV: negative predictive value; PPV: positive predictive value; WLE: white light endoscopy.