Table 2.
Patients’ demographics at enrollment.
| Patients’ Demographics | DS-EGCG (Group 1; n = 14) | DS-CT (Group 2; n = 10) |
|---|---|---|
| Male/Female (%) | 57/43 | 50/50 |
| Karyotype | Full Trisomy 21 | Full Trisomy 21 |
| Chronological age (months, M ± DS) | 41 ± 26 | 37 ± 22 |
| Patients aged ≤2 years (n) | 7 | 5 |
| Patients aged 2–8 years (n) | 7 | 5 |
| General quotient mental age (months, M ± DS) | 22 ± 12 | 20 ± 5 |
| Congenital Heart Disease | 2/14 | 1/10 |
| Hypothyroidism (on L-Tyroxine therapy) | 2/14 * | 1/10 * |
| Coeliac disease | 0/14 | 0/10 |
| Obstructive sleep apnea (OSAS) | 2/14 § | 1/10 § |
| Hypoacusia | 0/14 | 0/10 |
| Visual impairment | 2/14 Ɨ | 2/10 ° |
DS-EGCG: DS children treated with EGCG; DS-CT: DS control group; * acquired hypothyroidism controlled by L-Tyroxine therapy; § mild OSAS diagnosed by polysomnography; Ɨ nystagmus; ° strabismus.