Table 1.
MIC of coumarin derivatives 10, 12a, 13, 14a–g, 15 and penicillin G against B. cereus, B. subtilis, S. aureus, E. coli, S. typhimurium.
| Compounds | R | MIC (µg/mL) | ||||
|---|---|---|---|---|---|---|
| Gram-Positive | Gram-Negative | |||||
| B. cereus | B. subtilis | S. aureus | E. coli | S. typhimurium | ||
| 10 | - | 128 | 128 | 64 | >128 | > 128 |
| 12 | 4-H | > 128 | > 128 | > 128 | >128 | > 128 |
| 13 | - | 32 | 128 | 64 | >128 | > 128 |
| 14a | 4-H | > 128 | > 128 | > 128 | >128 | > 128 |
| 14b | 4-F | > 128 | > 128 | > 128 | >128 | > 128 |
| 14c | 4-Cl | > 128 | > 128 | > 128 | >128 | > 128 |
| 14d | 4-Br | > 128 | > 128 | > 128 | >128 | > 128 |
| 14e | 2,5-diF | > 128 | > 128 | > 128 | >128 | > 128 |
| 14f | 4-CH3 | > 128 | > 128 | > 128 | >128 | > 128 |
| 14g | 4-OCH3 | > 128 | > 128 | > 128 | >128 | > 128 |
| 15 | - | > 128 | > 128 | > 128 | >128 | > 128 |
| penicillin G | - | 16 | 2 | 16 | 32 | 64 |