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SIRT1 signaling in the cell. SIRT1 is a well-known NAD+-dependent deacetylase that impacts several molecules to promote health. Abbreviations: STAT3: signal transducer and activator of transcription 3; NF-κB: NF-kappa B; Bax: bcl-2-associated X protein; FOXOs: forkhead box transcription factors; PPARγ: peroxisome proliferator-activated receptors; NAD+: oxidized nicotine adenine dinucleotide; NADH: reduced nicotine adenine dinucleotide.
