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. 2021 Mar 16;10(3):470. doi: 10.3390/antiox10030470

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effects of PTX-generated breast tumor cell debris on macrophage polarization. Murine BMDMs and live 4T1 breast cancer cells or those killed by PTX treatment were co-cultured for 24 h. After co-culture, the proportions of macrophages expressing TNF-α (A) and IL-12p40 (B) were analyzed by flow cytometry. **, *** Significantly different between groups compared (** p < 0.01; *** p < 0.001). NS; not significant.

Effects of PTX-generated breast tumor cell debris on macrophage polarization. Murine BMDMs and live 4T1 breast cancer cells or those killed by PTX treatment were co-cultured for 24 h. After co-culture, the proportions of macrophages expressing TNF-α (A) and IL-12p40 (B) were analyzed by flow cytometry. **, *** Significantly different between groups compared (** p < 0.01; *** p < 0.001). NS; not significant.