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Schematic structure of heat shock proteins (HSPs). HSPs have four conserved functional regions. In light blue, the N-terminal domain (called domain J); in purple/violet, the flexible region enriched in glycine/phenylalanine; in orange, the substrate-binding region (M region); and, in red, the C-terminal region. Adapted from Guerrero-Rojas and Guerrero-Fonsecaz, 2018 [40].
