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Anti-inflammatory activities of tested compounds.
| No. | THP-1 Cells | P. acnes | |
|---|---|---|---|
| IC50 (μM) | SC (μM) | MIC (μM) | |
| 1 | 1.46 ± 0.21 | 0–5 | >5 |
| 5 | 30.5 ± 0.2 | 0–40 | >40 |
| 6 | 37.2 ± 3.1 | 0–50 | >50 |
| 9 | 41.6 ± 1.3 | 0–50 | >50 |
| 10 | 46.2 ± 2.2 | 0–50 | >50 |
| 12 | 34.3 ± 1.6 | 0–50 | >50 |
| Tretinoin | 3.38 ± 0.28 | 0–50 | >50 |
SC: Safe concentration, indicating the concentration range of THP-1 cells viability over 80% treated by tested compounds.
