Table 4.
Composition, experimental vs. predicted value with percentage error of optimized PLM-loaded glycerosome formulation.
| Variables | Optimum Composition | Response | Observed Value of Response | Predicted Value of Response | Percentage Error |
|---|---|---|---|---|---|
| X1 | 15 mg | Y1 | 119.20 ± 15.67 | 110.53 | 8.18 |
| X2 | 4 mg | Y2 | 76.42 ± 9.98 | 74.09 | 3.14 |
| X3 | 26.8% w/v | Y3 | 79.43 ± 12.43 | 76.12 | 4.34 |
Predicted error (%) = (observed value − predicted value)/predicted value × 100%; X1, Phospholipid (mg); X2, Cholesterol (% v/v); X3, Glycerol, Y1, Vesicles size (nm); Y2, Entrapment efficiency; Y3, Drug permeation/Flux (μg/cm2/h).