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Simplified summary of trough concentrations to target associated with outcome’s improvement.
| Drug | Timing | Trough Drug Concentrations (μg/mL) Associated with Outcome’s Improvement | Outcome Measure |
|---|---|---|---|
| UST | Induction (Week 8) | >3–7 | Clinical |
| UST | Maintenance | >1–3 | Clinical/Endoscopic |
| VDZ | Induction (Week 6) | >33–37 | Clinical/Endoscopic |
| VDZ | End of induction (Week 14) |
>15–20 | |
| VDZ | Maintenance | >10–15 | Clinical/Endoscopic |
