Table 1.
The combination index (CI) of BBR and DDP was calculated for the MG-63 cells.
| 24 h | 48 h | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| NO. | BBR (μM) |
DDP (μM) |
FA * | CI | NO. | BBR (μM) |
DDP (μM) |
FA * | CI |
| 1 | 2.5 | 1.25 | 0.191 | 0.856 | 1 | 2.5 | 1.25 | 0.331 | 0.893 |
| 2 | 2.5 | 2.5 | 0.245 | 0.625 | 2 | 2.5 | 2.5 | 0.394 | 0.829 |
| 3 | 2.5 | 5 | 0.290 | 0.628 | 3 | 2.5 | 5 | 0.450 | 0.941 |
| 4 | 2.5 | 10 | 0.346 | 0.729 | 4 | 2.5 | 10 | 0.540 | 1.052 |
| 5 | 5 | 1.25 | 0.221 | 1.132 | 5 | 5 | 1.25 | 0.491 | 0.928 |
| 6 | 5 | 2.5 | 0.279 | 0.769 | 6 | 5 | 2.5 | 0.515 | 0.678 |
| 7 | 5 | 5 | 0.309 | 0.778 | 7 | 5 | 5 | 0.559 | 0.759 |
| 8 | 5 | 10 | 0.393 | 0.685 | 8 | 5 | 10 | 0.619 | 0.859 |
| 9 | 10 | 1.25 | 0.291 | 1.126 | 9 | 10 | 1.25 | 0.518 | 0.790 |
| 10 | 10 | 2.5 | 0.371 | 0.668 | 10 | 10 | 2.5 | 0.613 | 0.666 |
| 11 | 10 | 5 | 0.412 | 0.609 | 11 | 10 | 5 | 0.677 | 0.581 |
| 12 | 10 | 10 | 0.454 | 0.645 | 12 | 10 | 10 | 0.793 | 0.632 |
* FA (fraction affected) represents the inhibitory rate of the drug on the MG-63 cells.