Table 5.
Comparison of results between spEnhancer and the three existing methods on the independent test dataset.
| Methods | Acc | Sn | Sp | MCC | AUC | |
|---|---|---|---|---|---|---|
| enhancers vs non-enhancers |
spEnhancer | 0.7725 | 0.8300 | 0.7150 | 0.5793 | 0.8235 |
| iEnhancer-ECNN | 0.7690 | 0.7850 | 0.7520 | 0.5370 | 0.8320 | |
| iEnhancer-EL | 0.7475 | 0.7100 | 0.7850 | 0.4964 | 0.8173 | |
| iEnhancer-2L | 0.7300 | 0.7100 | 0.7500 | 0.4604 | 0.8062 | |
| EnhancerPred | 0.7400 | 0.7350 | 0.7450 | 0.4800 | 0.8013 | |
| strong enhancers vs weak enhancers |
spEnhancer | 0.6200 | 0.9100 | 0.3300 | 0.3703 | 0.6253 |
| iEnhancer-ECNN | 0.6780 | 0.7910 | 0.7480 | 0.3680 | 0.7480 | |
| iEnhancer-EL | 0.6100 | 0.5400 | 0.6800 | 0.2222 | 0.6801 | |
| iEnhancer-2L | 0.6050 | 0.4700 | 0.7400 | 0.2181 | 0.6678 | |
| EnhancerPred | 0.5500 | 0.4500 | 0.6500 | 0.1021 | 0.5790 |