The effect of UCII on the serum lactate (A), myoglobin (B), osteocalcin (C), COMP (D), IL-1β (E), IL-6 (F), and TNFα (G) levels in exercised rats. Box and Whisker plots show median, min, and max values. ANOVA and Tukey’s post-hoc test were used to compare the results among different treatment groups. Statistical significance between groups is shown by: * p < 0.05, *** p < 0.001, **** p < 0.0001 compared as control group and, ##
p < 0.01, ####
p < 0.01 com-pared as exercise Group. UCII, Undenatured type II collagen; COMP, cartilage oligomeric matrix protein; IL-1β, interleukin-1β, IL-6, interleukin-6; TNFα, tumor necrosis factor-alpha. Control (Circle): no exercise and no UCII, E (Square): exercised rats, E + UCII (triangle), exercised rats receiving 4 mg/kg BW/day UCII.