Table 7.
Adipose Tissue | Bone Marrow | Amniotic Fluid | |
---|---|---|---|
rMSCs | PDT: approx. 2 days - Phenotype: CD29+; CD44+; CD73±; CD90±; CD105±; CD34±; CD45- - SOX2±; OCT4±; NANOG± - Differentiation potential: adipo-genic, osteogenic, chondrogenic, neurogenic [17,34,39,58,60,75,76,77,78,79] |
- PDT: approx. 5 days - Phenotype: CD29+; CD44+; CD73+; CD90+; CD105+; CD14-; CD34¬-; CD45- - SOX2±; OCT4±; NANOG± - Differentiation potential: adipogenic, osteogenic, chondrogenic, neurogenic [31,33,60,80,81] |
- PDT: approx. 3 days - Phenotype: CD29+; CD44+; CD73±; CD90±; CD105±; CD34 ¬-; CD45- - SOX2±; OCT4±; NANOG± - Differentiation potential: adipogenic, osteogenic, chondrogenic, neurogenic, cardiomyocytes [31,32,33,82,83,84,85] |
hMSCs | - PDT: approx. 2 days - Phenotype: CD29+; CD44+; CD73+; CD90+; CD105+; CD14-; CD31-; CD34¬-; CD45- - SOX2±; OCT4±; NANOG± - Differentiation potential: adipo-genic, osteogenic, chondrogenic, neurogenic, cardiomyocytes, endothelial cells [39,47,63,66,67,68,72,86,87] |
- PDT: approx. 6 days - Phenotype: CD29+; CD44+; CD73+; CD90+; CD105+; CD14-; CD34¬-; CD45- - SOX2±; OCT4±; NANOG± - Differentiation potential: adipogenic, osteogenic, chondrogenic, neurogenic [47,63,72,80,88] |
- PDT: approx. 2 days - Phenotype: CD29+; CD44+; CD73+; CD90+; CD105+; CD14-; CD34 ¬-; CD45- - SOX2±; OCT4±; NANOG± - Differentiation potential: adipogenic, osteogenic, chondrogenic, neurogenic, hepatocyte, epithelilal lung lineages, kidney lineage [40,87,89,90,91,92,93,94,95] |
rMSCs—rabbit mesenchymal stem cells; hMSCs—human mesenchymal stem cells; PDT- population doubling time; SOX2—sex determining region Y—box 2; OCT4—octamer-binding transcription factor 4; +—positive expression; -—negative expression; ±—expression differs among studies.