Table 1.
Side Effect | Incidence of Side Effects: Risk Ratio (95% CI) | Incidence of Side Effects: Multivariate Logistic Regression, Coefficient (p-Value) | Severity of Side Effects: Univariate Cumulative Risk Models (p-Value) | Severity of Side Effects: Multivariate Cumulative Risk Models (p-Value) |
---|---|---|---|---|
Any side effect | 1.08 (1.05–1.11) | 0.575 (0.004) | <0.001 | <0.001 |
Localized reaction | 1.10 (1.06–1.15) | 0.45 (0.003) | <0.001 | 0.003 |
Fever | 2.24 (1.86–2.70) | 0.876 (<0.001) | NS | NS |
Flu-like illness | 1.78 (1.51–2.10) | 0.658 (<0.001) | NS | NS |
Shortness of breath | 2.05 (1.28–3.29) | 0.651 (0.011) | NS | NS |
Skin rash | 1.04 (0.54–2.00) | NS | NS | NS |
Tingling | 1.26 (0.83–1.91) | NS | NS | NS |
Swelling | 1.00 (0.32–3.14) | NS | NS | NS |
Generalized swelling | 1.84 (0.94–3.60) | NS | NS | NS |
Anaphylaxis | 0.55 (0.06–4.72) | NS | NS | NS |
Fatigue or tiredness | 1.34 (1.2–1.49) | 0.418 (<0.001) | <0.001 | <0.001 |
Other | 1.46 (1.16–1.82) | 0.349 (0.013) | NS | NS |
Worse outcomes associated with a prior COVID-19 infection |