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. 2021 Mar 17;11(3):249. doi: 10.3390/life11030249

Table 2.

Differences in the incidence and severity of side effects among people who received an mRNA or a viral vector vaccine.

Side Effect Incidence of Side Effects: Risk Ratio (95% CI) Incidence of Side Effects: Multivariate Logistic Regression, Coefficient (p-Value) Severity of Side Effects: Univariate Cumulative Risk Models (p-Value) Severity of Side Effects: Multivariate Cumulative Risk Models (p-Value)
Any side effect 1.06 (1.01–1.11) NS <0.001 <0.001
Localized reaction 1.29 (1.19–1.40) 0.892 (<0.001) NS NS
Fever 0.28 (0.24–0.34) −1.993 (<0.001) <0.001 NS
Flu-like illness 0.34 (0.29–0.40) −1.795 (<0.001) <0.001 NS
Shortness of breath 0.43 (0.26–0.70) −0.853 (0.002) NS NS
Skin rash 0.86 (0.40–1.83) NS NS NS
Tingling 0.68 (0.43–1.09) NS NS NS
Swelling 0.29 (0.10–0.80) −1.326 (0.015) NS NS
Generalized swelling 0.29 (0.15–0.56) −1.423 (<0.001) NS NS
Anaphylaxis 0.19 (0.04–0.94) −1.890 (0.024) NS NS
Fatigue or tiredness 0.56 (0.51–0.62) −1.331 (<0.001) <0.001 NS
Other 0.67 (0.52–0.86) −0.471 (0.004) NS NS
mRNA vaccines superiority
Viral vector vaccines superiority