Table A5.
Side Effect | Incidence of Side Effects: Risk Ratio (95% CI) | Incidence of Side Effects: Multivariate Logistic Regression, Coefficient (p-Value) | Severity of Side Effects: Univariate Cumulative Risk Models (p-Value) | Severity of Side Effects: Multivariate Cumulative Risk Models (p-Value) |
---|---|---|---|---|
Any side effect | 1.01 (0.97–1.06) | NS | <0.001 | 0.025 |
Localized reaction | 0.99 (0.93–1.05) | NS | 0.002 | NS |
Fever | 1.19 (0.93–1.53) | NS | 0.009 | NS |
Flu-like illness | 1.07 (0.86–1.34) | NS | <0.001 | NS |
Shortness of breath | 1.73 (1.00–2.98) | –0.085 (0.03) | NS | NS |
Skin rash | 1.25 (0.59–2.65) | NS | NS | NS |
Tingling | 2.23 (1.45–3.42) | –0.114 (0.001) | NS | NS |
Swelling | 0.4 (0.05–3.03) | NS | NS | NS |
Generalized swelling | 0.72 (0.26–2.04) | NS | NS | NS |
Anaphylaxis | NA | NS | NS | NS |
Fatigue or tiredness | 1.17 (1.03–1.34) | NS | 0.009 | NS |
Other | 1.26 (0.96–1.66) | –0.043 (0.045) | NS | NS |
Worse outcomes: concerned |