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The structure of A1 monomer (A), dimer (B), and the surface charge feature of a dimer (C) (PDBid 6X91). A1 has a unique C-terminal domain A1HD (A1 hydrophobic domain) that mediates the protein-protein dimer formation. A long strip of positively charged surface is formed through dimerization, which may be used for recruiting nucleic acids or other protein partners.
