Table 1.
Characteristics and global adequacy of antimicrobial prescription between ASP and non-ASP units.
| Variables | ASP | Non-ASP | p Value |
|---|---|---|---|
| Characteristics of Units | |||
| Units N | 15 | 38 | − |
| Beds available N | 184 | 426 | − |
| Patients admitted/ Available beds n/N (%) |
117/184 (63.6) | 369/426 (86.6) | − |
| Medical Units n/N (%) | 5/15 (33.3) | 14/38 (36.8) | 0.81 |
| Surgical Units n/N (%) | 6/15 (40) | 19/38 (50) | 0.51 |
| Intensive Care Units n/N (%) | 4/15 (26.7) | 5/38 (13.2) | 0.24 |
| Characteristics of antibiotic prescriptions | |||
| Antibiotic prophylaxis n/N (%) | 14/117 (12) | 64/426 (17.3) | 0.17 |
| Antimicrobial therapy n/N (%) | 27/117 (23.1) | 103/426 (27.9) | 0.30 |
| Prescriptive appropriateness | |||
| Appropriate antimicrobial prescription n/N (%) | 27/41 (65.8) | 38/167 (22.7) | <0.001 |
| Inappropriate antimicrobial prescriptions n/N (%) | 14/41 (34.2) | 129/167 (77.2) | |
| Reason for inappropriate antimicrobial prescription | |||
| Antimicrobial unnecessary n/N (%) | 3/14 (21.4) | 50/129 (38.7) | 0.14 |
| Antimicrobial inadequate n/N (%) | 3/14 (21.4) | 14/129 (10.8) | 0.30 |
| Antimicrobial not recommended n/N (%) |
4/14 (28.6) | 46/129 (35.6) | 0.46 |
| Excessive duration n/N (%) | 3/14 (21.4) | 40/129 (31) | 0.36 |
| Inadequate dose n/N (%) | 4/14 (28.6) | 19/129 (14.7) | 0.24 |
| Inadequate way of administration n/N (%) |
0/14 (0) | 2/129 (1.5) | 0.62 |
| 2 reasons for inappropriate antimicrobial prescription n/N (%) | 3/14 (21.4) | 35/129 (27.1) | 0.53 |
| ≥3 reasons for inappropriate antimicrobial prescription, n/N (%) |
0/14 (0) | 3/129 (2.3) | 0.55 |