Table 2.
Multivariate Cox regression analyses for risk of second relapse and death.
| Variable | Association with Risk of Relapse | Association with Risk of Death | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p-Value | HR | 95% CI | p-Value | |
| Age | * | * | * | 1.03 | 1.00–1.05 | 0.04 |
| Stage I low risk (reference) | 1.0 | 1.0 | ||||
| Stage I intermediate risk | 1.93 | 0.86–4.35 | 0.112 | 1.27 | 0.69–2.36 | 0.44 |
| Stage I high risk | 5.60 | 2.36–13.27 | <0.001 | 3.68 | 1.83–7.42 | <0.01 |
| Stage II–III | 3.31 | 1.52–7.18 | 0.002 | 2.34 | 1.30–4.21 | 0.01 |
| External boost only (reference) | 1.0 | 1.0 | ||||
| Combined boost | 0.41 | 0.21–0.79 | 0.008 | 0.50 | 0.29–0.86 | 0.01 |
| VBT | 0.48 | 0.25–0.93 | 0.030 | 0.45 | 0.25–0.80 | 0.01 |
* Not significant in univariate analysis and therefore not included in the multivariate model.