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. 2021 Mar 17;22(6):3091. doi: 10.3390/ijms22063091

Figure 7.

Figure 7

CID16020046 inhibits O-1602-induced triglycerides accumulation in the liver. (A) Experimental protocol. HFD was fed to C57BL/6 mice for 4 weeks and O-1602 was administrated by i.p. injection three times per week for 4 weeks. CID16020046 was administrated by i.p. injection five times per week for the last week of 4-week treatment of HFD or O-1602. (B) Oil red O staining of liver sections. (C) Histograms of oil red O staining. The scale bar means 20 μm. (D) Liver/body weight ratio. (E) Triglycerids contents in serum. Green color means NCD, red color for HFD, red hatching or arrows for O-1602 administration, blue hatching or arrows for CID16020046 administration. Results are presented as the means ± SDs of 5 mice per group. * p < 0.05, ** p < 0.01, *** p < 0.001 vs. the NCD group; # p < 0.05, ## p < 0.01, vs. O-1602 group.