Table 2.

Activators of Different Inflammasomes.

Inflammasome	Activators
NLRP1b	B. anthracis lethal toxin, T. gondii, Muramyl dipeptide
NLRP3	C. albicans, S. cerevisiae, S. aureus, L. monocytogenes, Influenza virus, Sendai virus, Adenovirus, Bacterial pore-forming toxins, Hemozoin, Silica, Asbestos, Ultra violet (U.V.), ATP, Glucose, Monosodium urate (MSU) crystals, Calcium pyrophosphate dehydrate, β-amyloid, Aluminum particles (Alum), Imiquimod, Hyaluronan, ROS, Cholesterol crystals, Cell swelling
NLRC4	Cytosolic Flagellin, Type III secretion system (T3SS) rod protein, T3SS needle complex protein PrgI
NLRP6	Lipoteichoic acid, Gut metabolites, Microbial RNA, LPS
AIM2	dsDNA from DNA viruses or cytosolic bacteria
Pyrin	Bacterial toxins-inducing Rho guanosine triphosphatase (Rho GTPase) inhibition, such as the ones from C. difficile, H. somni, V. parahaemolyticus, or Y. pestis