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. 2021 Mar 18;11(3):543. doi: 10.3390/diagnostics11030543

Table 1.

Characteristics of patients who underwent the capsule endoscopy.

Total
N = 23
Positive Findings
n = 14
No Findings
n = 9
p-Value
Median age, range (years) 67 (31–83) 68 (31–83) 66 (42–79) 0.83
Male, no (%) 21 (91%) 14 (100%) 7 (78%) 0.044 *
BMI, kg/m2, range 19.6 (16–30.4) 21.6 (17.6–30.4) 17.9 (16–28.2) 0.10
ECOG PS, no (%) 0 8 (35%) 6 (43%) 2 (22%) 0.30
1 15 (65%) 8 (57%) 7 (78%)
Primary tumor, no (%) 0.28
Renal cell carcinoma 12 (52%) 8 (57%) 4 (44%)
Gastric cancer 6 (26%) 4 (29%) 2 (22%)
Esophageal cancer 2 (9%) 0 2 (22%)
Malignant melanoma 2 (9%) 1 (7%) 1 (11%)
MSI-H solid tumor 1 (4%) 1 (7%) 0
Immune checkpoint inhibitors, no (%) 0.32
Nivolumab 20 (87%) 11 (79%) 9 (100%)
Pembrolizumab 2 (9%) 2 (14%) 0
Nivolumab plus ipilimumab 1 (4%) 1 (7%) 0
Median Lichtiger score, range 0 (0–3) 0 (0–1) 0 (0–3) 0.38
NSAIDs usage, no (%) 6 (26%) 3 (21%) 3 (33%) 0.37
PPI usage, no (%) 8 (35%) 5 (36%) 3 (33%) 0.90
Baseline laboratory findings
WBC, range (/μL) 6400 (3500–13,700) 7000 (3500–13,700) 6200 (4200–7300) 0.20
Hb, range (g/dL) 12.4 (7.7–15.1) 12.6 (7.7–15.1) 12.2 (8.8–14.5) 0.70
CRP, range (mg/dL) 0.25 (0.01–2.8) 0.16 (0.01–2.8) 0.1 (0.01–1.55) 0.42

Abbreviations: BMI, body mass index; CRP, C-reactive protein; ECOG, European cooperative oncology group; Hb, hemoglobin; MSI-H, microsatellite instability-high; NSAIDs, nonsteroidal anti-inflammatory drugs; PPI, proton pump inhibitors; PS, performance status; WBC, white blood cell. One asterisk (*) indicates p value smaller than 0.05 (p < 0.05).