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. 2021 Mar 19;26(6):1718. doi: 10.3390/molecules26061718

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effects of OPA on cytokines in serum (A–F) and colon tissues (G–L). Levels of IFN-γ (A), IL-2 (B), TNF-α (C), IL-10 (D), IL-4 (E), and Th1/Th2 (F) in serum and levels of IFN-γ (G), IL-2 (H), TNF-α (I), IL-10 (J), IL-4 (K), and Th1/Th2 (L) in colon tissues. Con was control group, M was model group, H was the high dose OPA group, L was low dose OPA group, P was positive group. Data were expressed as the mean ± SD (n = 6), the statistical analyses were done with t-test; *** p < 0.001, ** p < 0.01, * p < 0.05 compared with the model group; ^### p < 0.001, ^## p < 0.01, ^# p < 0.05 compared with the control group.