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Organization of the 2,4-DAPG biosynthetic cluster and current understanding of the biosynthesis scheme. (A) Organization of the phl biosynthetic gene cluster found in DAPG-producing Pseudomonas spp. (B) Current understanding of the biosynthesis and degradation of DAPG in the genus Pseudomonas. MAPG ATase is an enzyme multiplex composed of PhlA, PhlB and PhlC units. Abbreviations are as follows: MAPG, monoacetylphloroglucinol; DAPG, 2,4-diacetylphloroglucinol.
