Table 2.
Technical aspects of 18F-PSMA-1007 PET/CT in the included studies.
| Authors | Hybrid Imaging Modality | Fasting/Hydration before Radiotracer Injection | Mean Radiotracer Injected Activity (MBq) (Range) | Time Interval between Radiotracer Injection and Image Acquisition (Minutes) | PET/CT Scan Extension | Image Analysis | Other Imaging Performed for Comparison |
|---|---|---|---|---|---|---|---|
| Anttinen et al. [24] | PET/CT with low-dose CT | NR/NR | 263 ± 27 (205–355) | 60 | From vertex to mid-thigh | visual and semi-quantitative (SUVmax) | Planar scintigraphy and SPECT/CT with 99mTc-diphosphonates, CT, WBMRI with DWI |
| Giesel et al. [25] | PET/CT with low-dose CT | NR/NR | 275 (111–356) | 60 + 180 | NR | visual and semi-quantitative (SUVmax) | – |
| Giesel et al. [26] | PET/CT with low-dose CT | 4 h/NR | 240–260 | 120 | From vertex to thighs | visual and semi-quantitative (SUVmax) | 18F-DCFPyL PET/CT |
| Hong et al. [27] | PET/CT with low-dose CT | NR/NR | 4 MBq/kg; 291 (185–366) | 120 | From skull base to mid-thigh | visual and semi-quantitative (SUVmax) | – |
| Kesch et al. [28] | PET/CT with low-dose CT | NR/NR | NR | 60 + 180 | NR | visual and semi-quantitative (SUVmax) | multi-parametric MRI |
| Kuten et al. [29] | PET/CT with low-dose CT | NR/yes | 4 MBq/kg | 60 | From vertex to mid-thigh | visual and semi-quantitative (SUVmax) | 68Ga-PSMA-11 PET/CT |
| Privé et al. [30] | PET/CT with contrast enhanced CT | NR/yes | ~250 | 90 ± 10 | NR | visual and semi-quantitative (SUVmax) | multi-parametric MRI |
| Sprute et al. [31] | PET/CT with low-dose CT | NR/NR | 270 | 90 (47–169) | NR | visual and semi-quantitative (SUVmax) | – |
Legend: CT = computed tomography; DWI = diffusion weighted imaging; MBq = MegaBecquerel; MRI = magnetic resonance imaging; NR = not reported; PET/CT = positron emission tomography/computed tomography; SPECT = single photon emission computed tomography; SUVmax = maximal standardized uptake value; 99mTc = technetium-99m; WBMRI = whole-body magnetic resonance imaging.