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The ratio of the transmembrane current induced by the antimycotics in the presence and absence of 50 μM of dioscin and uvaol. The SrE modified lipid bilayers were composed of DPhPC and bathed in 0.1 M KCl (pH 7.4) and NyS-altered bilayers were formed from DPhPC/CHOL (67/33 mol%) and bathed in 2 M KCl (pH 7.4).
| Compound | SrE | NyS |
|---|---|---|
| dioscin | 19.1 ± 6.8 | 1.0 ± 0.1 |
| uvaol | 1.1 ± 0.1 | 0.8 ± 0.1 |
