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. 2021 Mar 20;11(3):886. doi: 10.3390/ani11030886

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Immunohistochemical staining of cysteine aspartate specific protease-3 (cleaved caspase-3) in the cardiac cells of the experimental rats (IHC, ×400). A control (a), DPPE-treated (b) DOX-treated (c) and DPP + DOX-treated (d) rats. (e) Quantification of caspase-3 expression, the immunohistochemical staining of cleaved caspase-3 was measured as area percent (%) across 10 different fields/section, n = 7 rat/group. Mean values were statistically different from the CTR (^# p < 0.05), DPPE (* p < 0.05), and DOX (^$ p < 0.05) groups.