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. 2021 Mar 20;22(6):3184. doi: 10.3390/ijms22063184

Figure 1.

Figure 1

Transmission electron microscopy and characterization of exosomes from plasma of COVID-19 patients. (A) Representative transmission electron microscopy (TEM) image of exosomes isolated from COVID-19 patient plasma. The sample grids were screened under a JEOL JEM-1400Plus transmission electron microscope. The exosomes were round in shape with diameters of 30–70 nm. (B) Exosome lysates from plasma of normal and COVID-19 patients were subjected to Western blot analysis for detection of CD63 and TSG101 protein using specific antibodies. A representative image shows results from normal and COVID-19 exosomes (1A, 12A, 19, and 20). Exosome depleted serum was used as a negative control.