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Endoglin in physiology and pathology. Scheme depicting how endoglin is associated with many physiological and malignant processes and might be a reliable biomarker and a therapeutic target depending on the cellular context. Transforming growth factor β (TGFβ), transforming growth factor β receptor II (TGFβRII), bone morphogenic protein (BMP), activin-like kinase (ALK), monoclonal antibody (MAb), matrix metalloproteinase 14 (MMP14), soluble endoglin (Sol-ENG).
