aa |
Amino acids |
ADCs |
Antibody-drug conjugates |
ADT |
Androgen signaling deprivation therapy |
AEs |
Adverse events |
AKT |
Protein kinase B |
ALK |
Activin-like kinase |
AuNPs |
Gold nanoparticles |
BM |
Bone marrow |
BMP |
Bone morphogenic protein |
CA |
Cancer antigen |
CAF |
Cancer-associated fibroblast |
co-SMAD |
Common partner SMAD |
CRC |
Colorectal cancer |
Cys |
Cysteine |
EC |
Endothelial cell |
E-cadherin |
Epithelial cadherin |
ECM |
Extracellular matrix |
ELISA |
Enzyme-linked immunosorbent assay |
ENG |
Endoglin |
eNOS |
Endothelial nitric oxide synthase |
ERK |
Extracellular signal-regulated kinase |
EV |
Extracellular vesicle |
F-actin |
Filamentous-actin |
FAK |
Focal adhesion kinase |
GAIP |
G alpha interacting protein |
GDF |
Growth differentiation factor |
GIPC |
GAIP-interacting protein C-terminus |
HCC |
Hepatocellular carcinoma |
HER2 |
Human epidermal growth factor receptor 2 |
HHT |
Hereditary hemorrhagic telangiectasia |
HSC |
Hematopoietic stem cell |
ICAM-1 |
Intercellular adhesion molecule 1 |
IGF |
Insulin growth factor |
IL |
Interleukin |
IMVD |
Intratumoral microvessel density |
iRNA |
RNA interference |
JNK |
c-Jun N-terminal kinase |
MAPKs |
Mitogen activated protein kinases |
MMP |
Matrix metalloproteinase |
mRCC |
Metastatic renal cell carcinoma |
mRNA |
Messenger RNA |
MSC |
Mesenchymal stem cell |
MVs |
Microvesicles |
NO |
Nitric oxide |
OPN |
Osteopontin |
ORR |
Overall response rate |
OS |
Overall survival |
PDZ |
PSD-95/Discs-large/ZO1 |
PET |
Positron emission tomography |
PFS |
Progression free survival |
PI3K |
Phosphatidylinositol-3-kinase |
PR |
Partial response |
RCC |
Renal cell carcinoma |
RGD |
Arginine-glycine-aspartic acid |
RhoA |
Ras homolog family member A |
ROCK |
Rho-associated coiled-coil kinase |
R-SMAD |
Receptor-regulated SMAD |
SD |
Stable disease |
Ser |
Serine |
siRNA |
Small interfering RNA |
SIRT1 |
Sirtuin 1 |
SMA |
Serine-methionine-alanine |
Sol-ENG |
Soluble endoglin |
Sp1 |
Specificity protein-1 |
TAM |
Tumor-associated macrophage |
TGFβ |
Transforming growth factor β |
TGFβRI |
TGFβ type-I receptor |
TGFβRII |
TGFβ type-II receptor |
Thr |
Threonine |
TME |
Tumor microenvironment |
TNFα |
Tumor necrosis factor α |
TRAMP |
Transgenic adenocarcinoma mouse prostate |
Treg |
Regulatory T cell |
VCAM-1 |
Vascular cell adhesion molecule-1 |
VEGF |
Vascular endothelial growth factor |
VEGFR |
Vascular endothelial growth factor receptor |
VSMC |
Vascular smooth muscle cell |
WNT |
Wingless/Integrated |
ZP |
Zona pellucida |
ZRP1 |
Zyxin-related protein 1 |