Table 1.

Mean of DNA methylation values (and standard deviation) of CpG sites located within the analysed genes in HMCLs (MM1s, KMS11) and normal control cells (PBMCs). HMCLs, human myeloma cell lines; FDR: False Discovery Rate.

	MM1s	KMS11	Normal Control Cells	MM1s vs. Normal Control Cells		KMS11 vs. Normal Control Cells
Gene				p-Value	FDR	p-Value	FDR
COX10	0.353 (0.003)	0.331 (0.009)	0.528 (0.014)	3.57 × 10−6	1.67 × 10−5	2.91 × 10−6	1.36 × 10−5
COX18	0.054 (0.003)	0.058 (0.006)	0.068 (0.007)	0.134	0.250	0.406	0.421
DNM1L	0.071 (0.002)	0.056 (0.002)	0.065 (0.003)	0.796	0.872	0.101	0.129
FIS1	0.091 (0.014)	0.104 (0.007)	0.082 (0.009)	0.766	0.872	0.188	0.229
KIF5B	0.043 (0.006)	0.056 (0.003)	0.044 (0.003)	0.473	0.698	0.055	0.077
MAP1LC3A	0.760 (0.007)	0.836 (0.005)	0.262 (0.009)	8.45 × 10−16	7.89 × 10−15	6.67 × 10−14	9.34 × 10−13
MARCH5	0.068 (0.003)	0.081 (0.006)	0.057 (0.002)	0.052	0.120	8.09 × 10−4	0.002
MFN1	0.090 (0.014)	0.105 (0.009)	0.052 (0.003)	0.003	0.008	2.22 × 10−5	7.76 × 10−5
MFN2	0.064 (0.004)	0.075 (0.007)	0.057 (0.004)	0.177	0.292	0.029	0.046
MTERF	0.058 (0.009)	0.159 (0.008)	0.043 (0.005)	0.939	0.939	1.24 × 10−8	6.93 × 10−8
MTERFD1	0.091 (0.004)	0.086 (0.009)	0.056 (0.003)	1.29 × 10−6	7.24 × 10−6	0.001	0.002
MTIF2	0.053 (0.01)	0.057 (0.004)	0.039 (0.009)	0.143	0.250	0.213	0.249
MTIF3	0.064 (0.008)	0.074 (0.008)	0.049 (0.002)	0.029	0.075	0.002	0.003
POLG1	0.492 (0.014)	0.525 (0.003)	0.510 (0.008)	0.133	0.250	0.235	0.254
POLG2	0.060 (0.002)	0.070 (0.009)	0.036 (0.003)	4.14 × 10−5	1.45 × 10−4	9.26 × 10−4	0.002
POLRMT	0.066 (0.002)	0.060 (0.005)	0.027 (0.005)	9.73 × 10−6	3.89 × 10−5	0.003	0.005
RAB32	0.358 (0.003)	0.596 (0.015)	0.079 (0.006)	3.15 × 10−19	8.8 × 10−18	5.21 × 10−14	9.34 × 10−13
RHOT1	0.042 (0.003)	0.048 (0.007)	0.037 (0.002)	0.809	0.872	0.082	0.109
TFAM	0.065 (0.004)	0.076 (0.003)	0.047 (0.003)	0.894	0.927	1.37x10−4	4.27 × 10−4
TFB1M	0.103 (0.002)	0.168 (0.008)	0.088 (0.006)	0.653	0.831	1.29x10−5	5.15 × 10−0.5
TFB2M	0.090 (0.010)	0.077 (0.009)	0.074 (0.009)	0.556	0.779	0.850	0.850