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. 2021 Mar 21;13(3):1017. doi: 10.3390/nu13031017

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effects of B. adolescentis supplementations on immunity. (A–E) Relative mRNA expression of immune-related cytokines in the spleen, (A) interleukin 17F (Il-17f), (B) tumor necrosis factor α (Tnf-α), (C) forkhead box P3 (Foxp3), (D) Il-10, and (E) Il-4. (F–H) Concentrations of cytokines in the brain, (F) IL-17, (G) IL-6, and (H) IL-10. (I–K) Relative mRNA expression of immune-related cytokines in the hypothalamus, (I) Foxp3, (J) Il-6, and (K) toll-like receptor 4 (Tlr4). (L) The concentration of cytokine IL-10 in the abdominal white adipose tissue (aWAT). Data are shown as means ± standard deviations (SD). Asterisks indicate significant differences (one-way ANOVA, * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001). n = 6 or n = 5 (for (A–E,I–K)) mice per group.