Table 3.
Factors associated with unplanned hospitalizations on univariable analysis.
| Variable | UH (n = 184) n% |
Non-UH (n = 309) n% |
OR (95% CI) | p Value |
|---|---|---|---|---|
| Stage | ||||
| IV | 118 (64) | 166 (56) | 1.54 (1.06–2.24) | 0.024 |
| I–III | 66 (36) | 143 (44) | ||
| MAX2 index | ||||
| ≥1 | 138 (75) | 205 (66) | 1.52 (1.02–2.29) | 0.044 |
| 0 | 46 (25) | 104 (34) | ||
| Chemotherapy | ||||
| Standard therapy | 98 (53) | 117 (38) | 1.91 (1.32–2.76) | 0.001 |
| Reduced/monotherapy | 86 (47) | 192 (62) | ||
| Albumin g/dL | ||||
| ≤3.5 | 51 (28) | 30 (10) | 3.61 (2.21–5.92) | <0.001 |
| >3.5 | 133 (72) | 279 (90) | ||
| Creatinine Clearance mL/min | ||||
| <50 | 87 (47) | 106 (34) | 1.75 (1.20–2.54) | 0.03 |
| ≥50 | 97 (53) | 203 (66) | ||
| Unintentional weight loss % | ||||
| >5% | 80 (43) | 69 (22) | 2.67 (1.80–3.97) | <0.001 |
| ≤5% | 104 (57) | 240 (78) | ||
| ECOG PS | ||||
| 2 | 35 (19) | 28 (9) | 2.36 (1.38–4.03) | 0.02 |
| 0–1 | 149 (81) | 280 (91) | ||
| Charlson comorbidity score | ||||
| ≥2 | 84 (45) | 101 (33) | 1.73 (1.18–2.51) | 0.004 |
| 0–1 | 100 (55) | 208 (67) | ||
| ADL | ||||
| ≤5 | 52 (28) | 54 (17) | 1.87 (1.21–2.89) | 0.005 |
| 6 | 132 (72) | 255 (83) | ||
| IADL | ||||
| ≤7 | 87 (47) | 187 (60) | 1.71 (1.18–2.47) | 0.004 |
| 8 | 97 (53) | 122 (40) | ||
| Falls in the past 6 months | ||||
| ≥1 | 45 (24) | 39 (13) | 2.24 (1.39–3.60) | 0.01 |
| None | 139 (76) | 270 (87) |
Abbreviations: UH, unplanned hospitalization; ECOG PS, Eastern Cooperative Oncology Group performance status; ADL, activities of daily living; IADL: instrumental activities of daily living; Variables not reaching significance were age, sex, type of tumor, Short Physical Performance Battery (SPPB), body mass index, Pfeiffer test, Hospital Anxiety and Depression Scale (HDAS score), MOS Social Support Survey, Vulnerable Elders Survey-13 (VES-13), creatinine clearance, hemoglobin, and platelets and neutrophils counts.