Table 1.

Examples of Cas9 protein orthologs.

Ortholog	Host Organism	PAM Sequence (5′→3′)	References
NmeCas9	Neisseria meningitidis	NNNNG(A/C)TT	[38]
SaCas9	Staphylococcus aureus	NNGRRT or NNNRRT	[39]
St1Cas9	Streptococcus thermophilus	NNAGAA or NNAGAAW	[40]
ScCas9	Streptococcus canis	NNG	[41]
CjCas9	Campylobacter jejuni	NNNNACA	[42]
FnCas9	Francisella novicida	YG	[43]
St2Cas9	Streptococcus thermophilus	NGGNG	[44]