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Bacterial DNA assessed using 16S rRNA gene qPCR in study groups. a Human samples sign. exceeded mouse and negative controls in terms of 16S rRNA gene copy numbers, most likely resulting from the differentially handled putamen samples (PK2 in C). b Bacterial DNA did not differ between human samples (PD, HC, and SC). PD, Parkinson; HC, healthy control; SC, sterile brain from healthy living volunteers. *16S rRNA gene copies post off-target amplicon and contaminant removal
