Table 2.
POCS miRNA set, present in all PDAC organoid EVs, shows a complete overlap with PDAC blood EVs and a partial overlap with PDAC cell line (Panc10.05, Panc08.13)-derived EV cargo (cultured in Matrigel)
| POCS | Presence in EVs in … | ||
|---|---|---|---|
| All PDAC organoid supernatants | All PDAC cell line supernatants | All PDAC plasma samples | |
| hsa-miR-146a | ✓ | Only in Panc08.13 | ✓ |
| hsa-miR-16 | ✓ | ✓ | ✓ |
| hsa-miR-24 | ✓ | ✓ | ✓ |
| hsa-miR-320 | ✓ | Only in Panc08.13 | ✓ |
| hsa-miR-192 | ✓ | Only in Panc10.05 | ✓ |
| hsa-miR-222 | ✓ | ✓ | ✓ |
| hsa-miR-21 | ✓ | ✓ | ✓ |
| hsa-miR-19b | ✓ | ✓ | ✓ |