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(a) Chemical structure of pBODO-PEG-VR and preparation of APNA. (b) Mechanism of antitumor immune response by APNA-mediated NIR-II photothermal immunotherapy. TAAs tumor-associated antigens, DAMPs damage-associated molecular patterns, iDC immatureDC, mDC mature DC, HMGB1 high-mobility group box 1 protein (Reprinted Permission from Nature, 2021 under creative common license) [76].
