Table 1.
Serum biochemical parameters and lipid peroxidation in rats. *, ** and *** indicate a statistically significant difference with p < 0.05, p < 0.01, and p < 0.001, respectively, for the control group.
| Item | Treatment | |||
|---|---|---|---|---|
| Control | Curcumin Microemulsion 30 mg/kg | Thioacetamide 100 mg/kg | Thioacetamide 100 mg/kg + Curcumin 30 mg/kg |
|
| AST (U/L) | 78.0 ± 8.6 | 66.3 ± 10.0 | 96.7 * ± 15.0 | 77.8 ± 11.7 |
| ALT (U/L) | 31.1 ± 4.7 | 36.2 ± 4.1 | 48.3 ** ± 9.6 | 41.2 * ± 8.1 |
| MDA (nmol/mL) | 137.9 ± 20.8 | 130.6 ± 21.0 | 164.0 * ± 21.5 | 141.7 ± 13.1 |
| BUN (mg/dL) | 14.3 ± 2.8 | 13.8 ± 2.0 | 24.2 *** ± 4.5 | 15.2 ± 1.6 |
| Creatinine (mg/dL) | 0.95 ± 0.17 | 1.1± 0.21 | 2.01 *** ± 0.39 | 1.20 ± 0.48 |
| Liver SOD (U/g protein) |
18.0 ± 2.3 | 26.0 ** ± 8.0 | 11.7* ± 2.2 | 16.5 ± 2.4 |
| Liver CAT (U/g protein) |
52.5 ± 8.4 | 62.9 * ± 79.9 | 38.1 ** ± 7.4 | 44.5 ± 6.8 |