Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 22;13(6):1443. doi: 10.3390/cancers13061443

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Activity of NK-92/5.28.z cells against aRMS tumor spheroids. Tumor spheroids were established from RH30 (A) and RH41 cells (B,C). NK-92/5.28.z or NK-92 cells were added as effector cells at an E:T ratio below 1:1, and their growing and antitumoral activity were followed over 10 days. NK-92/5.28.z cells exhibited fast and efficient lysis of aRMS tumor spheroids within two (A,B) to five days (C, fewer effector cells), while parental NK-92 cells were not able to efficiently lyse the tumor cells in 3D culture. Growing behaviors of target and effector cells (D) alone as well as in cocultures are shown in parallel, which allows for discrimination between tumor and effector cells.