Table 1.

Comparison of preclinical animal model features.

Model	Tumor Source	Immune Status	Cost	Labor/Time
CLX	Human	(−)	$	+
PDX	Human	(−)	$$	++
Syngeneic	Mouse	(+)	$	++
GEMM	Mouse	(+)	$$$	+++

CLX, cell-line xenograft; PDX, patient-derived xenograft; GEMM, genetically engineered mouse model.