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. 2021 Mar 23;10(3):712. doi: 10.3390/cells10030712

Table 3.

Glioma patient-derived xenograft (PDX) murine models.

Mouse Species Brain Tumor Modeled Source of Tumor Cells Reference
eGFP NOD/SCID mice Oligodendroglioma Patient-derived tumor cells [108]
NOD-PrkdcSCID IL2Rγnull Grade II-IV Glioma Patient-derived glioma tissue [109]
NOD-SCID Malignant Astrocytoma Embryonic stem cells [110]
Glioma Patient-derived high grade glioma tissue [111]
NOD/SCID Il2rg−/− (NOG) GBM Patient-derived GBM cells [112]
Not reported GBM Patient-derived human GBM cells [113]
NSG GBM Patient-derived GBM neuro-spheres [114]
Nude Glioma Patient-derived IDH mutant glioma tissue [115]
GBM Patient-derived GBM tissue [116,117]
GBM Patient-derived GBM tissue [28,118]
SCID IDH Mutant Glioma Patient-derived glioma neuro-spheres [119]
IDH1 Mutated Glioma GBM164, GBM196, and TB09 IDH1 mutant glioma PDX models [120,121]